A: Although the microorganism is very small, but it still has volume, so any product, the number of bacteria will limit by space. When the number of bacteria is too high, more than the tolerable density, the stability of the live bacteria began to decline, like a narrow space, crowded with too many people, people will feel uncomfortable. Therefore, a good probiotic product, must screen the most useful strains and cultured to the most suitable quantity for maximum effectiveness.
A: The benefits of probiotic products come from probiotics themselves, or their metabolites. The benefits of probiotics themselves, including the characteristics of probiotics (e.g. reproduction), and the bacteria “body”. The benefits from bacteria body and metabolites is no difference irrespective of the bacteria is live or dead.But the benefits because of strong reproductive capacity to inhibit the growth of bad bacteria, or eliminate the pollutants during reproducing process, it is must be live bacteria. For example, the common function of Bacillus spores, will produce antibacterial peptides. These antimicrobial peptides has been produced in the production process, so live bacteria and dead bacteria, did not have much impact on the effect. But another function of bacillus spores is to compete the oxygen or other nutrition with the bad bacteria, it is must be live. Also, many lactic acid bacteria can fight against bad bacteria by some mechanism, such as "knock out" the bad bacteria, live bacteria and dead bacteria are no different. One of the advantages of yeast is that the bacteria themselves have a lot of nutrition, and the dead bacteria are more easy to be released and absorbed than live bacteria. Therefore, live bacteria, dead bacteria who are more effective should be case by case.
A: Good bacteria or bad bacteria may be resistant to antibiotics. We hope that good bacteria are not afraid of antibiotics, but bad bacteria are afraid in direct feeling. But whether good or bad bacteria, they can be transmit genetic information. in other words, the ability to resist antibiotics, may be transmitted. Therefore, probiotics are not encouraged to be used in combination with antibiotics, or even restrict the use of antibiotic combine with probiotics, not for fear that antibiotics will kill probiotics, or probiotics affect the use of antibiotics, but to avoid the "drug-resistant" gene from probiotics to pathogenic bacteria, resulting all the medicine are void in the future. For antibiotics and probiotics, humans should not pursue antibiotic-resistant probiotics, but should establish the right idea that when antibiotics are used. Good bacteria and bacteria can be killed, but good bacteria continue to supplement, making bad bacteria has no chance of survival.
A: The temperature tolerance of each strain is different in probiotic. Some probiotics that can produce spores are generally better heat tolerance, but such as lactic acid bacteria we commonly used are less heat-tolerance. Therefore, probiotics should pay attention to temperature, pressure and time through the "thermal process", and product preservation should avoid high temperatures as much as possible.
A: Intestinal bacteria (normal flora or gut bacteria) refer to normal flora present in the intestines of animals, some bacteria cannot be settled and colonized in the intestines, we call it “passer bacteria” here. General speaking, bad bacteria has fimbriae, it is easy to colonize in the intestines, but good bacteria do not have fimbriae, so can not colonize. But some specific strains, such as bifidobacterium, will metabolic adhesion "sticky" in the intestines and colonize. And our company's products Full probio, mainly the use of biffidobacterium longums settled in the large intestine, lactobacillus acidophilus settled in the small intestine, in order to achieve complete protection of the intestine. In addition, such as bacillus, yeast, is a passer bacteria, although not long time attachment to the intestines, but still play a number of important functions, such as maintaining the anaerobic environment in the intestine, providing nutrition, metabolic enzymes, antibacterial peptides and so on. In addition, these passers bacteria which are excreted with feces, still play important functions even after excretion, such as decomposing feces and reducing pollution.
A: Now we often heard that "expanding culture" or "activation" is fermentation actually, the same as microbial culture by the factory . The difference is that equipment of the factory is perfect, raw material formulation precision and control strictly, but users themselves to expand culture, limited by environment and simplify process, so the results must not be as ideal as the factory, and exist a certain degree of risk. So the users should establish the correct concept if he would like to “expansion” of culture,
1. What is the purpose of the “expansion culture”?
(1) Products since the factory produced to the user bought it, may be spend for a long time, the physiological activity of live bacteria may be decline. Live bacteria began to wake up slowly if we use it direct. In normal case, the product can exert the function, but in some special case, such as the environment is too bad, or the probiotic must to fight against bad bacteria directly, we can't wait the probiotic wake up slowly then play the function, in such case, the “expansion culture” (or “activation”) is a good ideal. We can let probiotics wake up quickly, but pay attention that “not all probiotic can wake up at the same time, and fast wake-up bacteria may be not the one you need most.”
(2) The purpose of fermentation, sometimes not for the benefits of probiotics self, but the through fermentation, the nutrition of raw material is better absorption, such as the use of milk, milk as raw materials, milk nutrients can be absorbed by plants, if not fermented and direct use it, not only nutrients can not be absorbed, residual nutrients will also cause harm to the soil.
2. If you would like “expansion culture”, you should pay attention to the matters:
(1) the raw materials and tools of the culture may be not sterilized, so good bacteria is reproduction, bad bacteria is also reproduction, so all raw materials and tools , as possible as clean.
(2) The step of “expansion culture”, must attention that “the water and medium first mixed, then finally can add bacteria starter, can not be bacteria starter and medium mixed first, then finally add water.
(3) Do not retain the product of expanding culture as the bacteria starter when the next expansion culture, the risk is too great.
There are certain risks to the expanding culture, whether do it, users should carefully assess.
A: Products have powder and liquid two forms because convenience of used, for example the powder is more convenient when mixing with dry feed, and some users will mix feed and oil before feeding, then we can add liquid form in the oil before mixed with feed. In aquaculture, if we mix the powder form with grain feed first, when the feed throw into the pool, powder and grain feed will be dispersed, so liquid form adsorption in feed is more convenient. In addition to water treatment, environmental spraying, liquid form is also more convenient.
A: Probiotics are not medicine, should be used routinely. Do not use probiotics until the dangerous is become clear and present, it’s too late. Remember, the role of the probiotics is not treat problem as a arrow to hit the target , but to maintain a good environment, through the balance of good bacteria to achieve our purpose, in vitro and in vivo all the same. So the usual routine use probiotics, the establishment of good bacteria balance in vitro and in vivo, to avoid the emergence of crisis situation, is the purpose of the use of probiotics.