Antibiotics were widely used in feed Additives and have created miracle in husbandry industries in 20th century. However, it caused the hazard to human body with their residues in husbandry products with the drug resistance. For a long time, high pollution and antibiotics abuse have become the most serious lethal attack to husbandry industry. In view of this, Harmony Biotechnology Co., Ltd developed serial of high quality, natural, teoxic-free probiotic product "Full Probio®". The products base on favorable microbes and incorporated with biotechnologies. The uses of Full Probio® will effectively reduce the dosage of antibiotics and substitute the antibiotics. When it is used together with appropriate antibiotics, it will help to minimize the effect. To the animal husbandry, it is not only solve the problems which the growers are facing, it plays a vital role in the sustaining operation of animal husbandry.
Full Probio® serial products (Probiotic Feed Additive, Microbe Complex Liquid) are the products made through biotechnological process from favorable microbes, both of aerobe and anaerobe, including lactic acid bacteria, bifidobacterium，Saccharomyces cerevisiae, photo-synthetic bacteria and Bacillus subtilis to jointly co-exist in homogeneous culture media in active form and exert import effects.
Full Probio® can reduce the activeness of digestive bacteria inside the intestine of stock and poultry, promote the appetite of stock and poultry, strengthen their body feature, and can effectively reduce the odor of the ordure hence the bad smell in stock and poultry, improve the envi ronment, reduce the negative stimulus to stock and poultry, minimize disease and improve the quality of meat products.
1. Totally natural, free of side effects.
2. Reduce concentration of unpleasure order.
3. Resistance to disease, enhance health and vitality.
4. Reduce feed cost and breeding cost.
5. Boost the attraction of feeds.
6. Reduce diarrhea and cost in disease treatment.
7. Shorten growing days.
8. Increase in utilization rate of feed.
9. Substitute of antibiotics, effect expanded when
combining with antibiotics.
Domestic Animals: 1kg / Ton of Feed
Full Probio® of wearing pig growth performance
1.Full Probio®feed additive 、Oxytetracycline
2.Weaning pigs、Nursery pig feed
use 60 weaning pigs and 6-7 pigs per pen feedingand every groups pf three repeat.
1.Comparison group
2.Add 0.3% Full Probio® into feed
3.Oxytetracycline 300 ppm
1.Test one month，every day to observed and record : Clinical symptoms,uniformity and number of treatment.
2.Two weeks to weighting and scales feed，in order to growthperformance test，including :ADG，FI，F/G.
3.Death pigs pathological anatomy，microbiological testing and pathological diagnosis.
4.Related to detection antibody: when check- ing the start and end，take once per big blood.
5.Pig feces collection: test the concentration of H2S and NH3.
6.Vaccines: according to the test site immun- ization program :6 weeks old swinefever ，Erysipelas
7 weeks old FMD，Four vaccine.
Test unit : Growth performance in each column. Test data : SAS，General Linear Model Procedure and DMRT to Precess.
Growth performance: Feed Full Probio® effect
| Various stages |
Comparison of weight gain |
Full Probio® weight gain |
Oxytetra-cycline |
| Before test | 9.20 ± 0.43 | 9.45 ± 0.43 | 9.53 ± 0.44 |
| Mid-term test | 12.84 ± 0.48 | 13.44 ± 0.48 | 13.65 ± 0.49 |
| End test | 18.85 ± 0.72 | 21.13 ± 0.76 | 20.42 ± 0.73 |
| Before test to mid-term | 3.63 ± 0.24 | 3.99 ± 0.24 | 3.99 ± 0.24 |
| Mid-term to end test | 6.01 ± 0.40 | 7.40 ± 0.42 | 6.77 ± 0.41 |
| Before test to end test | 9.64 ± 0.46 | 11.51 ± 0.49 | 10.89 ± 0.47 |
The test to prove add 0.3% Full Probio® into the feed can :
1. raise the weight
2. through the weaning pig of urgency
3. reduce the incidence of desease
4. reduction of antibiotics
5. It can provide overall stop promoting alternative antibioticsAdded to nursery pig feed
1. By improving the environment, Full Probio® will change the bacteria composition inside the digestive ducts of poultry to provide advantage for favorable bacteria.
2. Using Full Probio® will allow the muscle of poultry to be stiff and increase yields.
3. Enhance growth and promote egg production.
4. Normal digestion, water consumption will maintain stable dry and reduce the concentration of H2S, ammonia and other odors.
5. Accelerate rapid weight increase and delayoestrus and reduce fighting between poultry.
6. Promote feed efficiency, shorten the breeding time.
7. Improve physical constitution of poultry and reduce the press, allowing the poultry to be free form the effect of change feeds, inoculation, as well as increase hardness of egg shell.
8. Grow in good condition, it will then keep the disease form occurring.
9. Save the cost of vitamin and antibiotics. Reduce diarrhea.
1 kg / Ton of Feed (Solid type)
1 L / Ton of drinking water (Liquid type)
For feeding the silky without using Full Probio® , feather pecking serious caused serious messy hair and dull.
Add liquid Full Probio® in drinking water.
1. Chicken weight gain of 10% to 15%.
2. Peck hair phenomenon obviously improved,and increase glossiness of chickens fur.
3. Reduce the incidence of parasites and increase incubation rate.
4. Reduce chicken manure odor and the number of flies.
5. Reduce respiratory tract infection. 《top》
Add liquid Full Probio®® in drinking water and add solid Full Probio® in feed.
1. Increase motility.
2. Increase the feeding rate.
3. Reduce fecal odor.
Add liquid Full Probio® in drinking water and add solid Full Probio® in feed. 1. Increase motility. 2. Increase the feeding rate. 3. Duck's body type are consistent.《top》
Add liquid Full Probio® in drinking water and add solid Full Probio® in feed.
1. Healthy Body.
2. Plumage with rich bright color.
The Fishing Crop of the world is traditionally covered salt water fishes, fresh water fishes, shrimps, seaweed and shellfishes. According to statistics in 1992, the global fishing crop had reached 98 million tons and this quantity has exceeds the ceiling nature can produce. With the climbing demand for aqua produce and decreas- ing natural fishing crop, UNFAO estimated the aquaculture needs to increase production to 52 million tons in 2010 and 77 million tons in 2025 to met the demand of aqua produce in the global market. It is easy to find that aquaculture is the necessary trend to meet the short supply in aqua produce in 21st Century, and it is an industry of global economic potential.
With the appropriate climate in Taiwan, aquaculture has been able to rot in Taiwan and diversified. Between 1960 and 1990, the aqua culturing production increased from 49,030 tons to 344,263 tons, more than 6 folds, and the aqua culture production between 1984 and 1993 accounted for 36.37% and is a quarter of the total fishing crop. From all these data, we can see the importance of aquaculture in Taiwan Fishing in- dustry. With the leaping demand of aquaculture, and after admission into WTO, aquaculture in- dustry is challenged in quality and quantity in economic standpoints.
By applying the new biotechnological techniques with favorable microbes, Harmony Biotechnology Co., Ltd has successfully developed Full Probio® serial products, Aquaculture Additives and Aqua Culture Feed Additives. They have the mission of revolutionary development in the quality and quantity of aquaculture produces and to satisfy the demand for aqua produce of the world.
The favorable microbe contained in Full Probio® can help in many different biochemical reactions to normalize the intestine duct of fishes and shrimps and maintain their health, increase immunity capacity to resist the attack of unfavorable bacteria. Full Probio® also has great effect in maintain good environment for aqua lives and improve their survival rate.
1. Allowing the microbe clusters in fishes and shrimps intestine duct normalized to keep them in healthy conditions.
2. Increase the immunity of fishes and shrimps and increase resistance to the unfavorable bacteria.
3. Rapid decomposition toxins like ammonia and hydrogen sulfide and reduce the concentration of nitride salt and boost the oxygen concentration in water.
4. Decomposing residual organic waste at the bottom of culturing pond and having the effect of purifying the bottom of culturing pond.
5. The digestive enzyme generated by active bacteria and vitamins is helpful to the growth of fishes and shrimps.
6. Stabilizing the water quality to fit for growth of fishes and shrimps.
7. Maintain good environment and boots surviv- ing rate in long term.
Depends on the fish and manner of culturing:
Generally 1kg / Ton of Feed
Purifying the culturing pond: 1kg for each 0.1 hectare
《top》
Table 1. The antagonistic spectra of Full Probio®
| Indicator strains |
Inhibitory zone diameter (mm) |
| Vibrio | |
| V. alginolyticus | 1.0 |
| V. anguillarum/td | 3.0 |
| V. cholerae | 4.0 |
| V. harveyi | 5.0 |
| V. parahaemolyticus | 3.0 |
| V. vulnificus | 3.0 |
| Escherichia | |
| E. coli BCRC 11549 |
3.0 |
| E. coli BCRC 11634 |
3.0 |
| Salmonella | |
| Salmonella typhimurium ATCC 14028 |
2.0 |
1. Raising water
(1) Aquaculture barrels for the first time used.
(2) Put the solid Full Probio® into the barrels , add water, not pump, then cultured one to three days. Eventually will get a good color.
(3) After using the pump to Increase the amount of dissolved oxygen, can begin aquaculture.
(1) Using liquid Full Probio® to cultivate rotifers and other organisms feed.
(2) Using liquid or solid Full Probio® to cultivate bloodworms and other organisms feed.
(1) Newly hatched Postlarvae.
(2) Put postlarvae into the ponds cultivated by solid Full Probio®.
(3) Postlarvae stable growth and survival rate of more than 70%.
(1) White egrets standing next to the pond to eat shrimp died due to poor water quality.
(2) Spilled liquid Full Probio® into poor water quality after three days, changing to the good color. ( Left – used /Right – unused )
1. Maintenance of water quality with the solid Full Probio® and regularly spilled liquid microbial products can make high density farming fry grow well.
2. Maintenance of water quality with the solid Full Probio® and regularly spilled liquid Full Probio® canmakeahealthyandvibrantfish.
1. Maintenance of water quality with the solid Full Probio® and regularly spilled liquid Full Probio® can make perch healthy、less can- nibalism and increase survival.
In the early stage, in order to increase the quantity of agricultural crops, chemical fertilizers were applies massively, but with the long term abuse and heavy reliance on them has caused high percentage residues of chemical substance and hardened and acid soil. The quality of crops and the disease resistance of plants are greatly hampered, leaving rooms for pests to damage. Full Probio® serial products developed by Harmony biotechnology—Microbe Soil Activator and Microbe Plant Growth Activating Complex Liquid is pure natural, toxin-free, harmless and free of residue bio agent. Long term application can improve the water retaining, permeability, of soil and adjust the pH value to be suitable for the growth of plants. The strengthened vitality of soil enables the crops to have higher resistance to disease and pest and help the adaptability to the natural environment.
1. Capable of improve the physical, chemical and biological property of solid and gain the synergy.
2. Improve soil structure to increase permeability.
3. It have the preventive effect on the hazard and that caused by nematoid.
4. Enhance the decomposition of organic material to increase the microbial cluster.
5. Promote the development of root system, strengthen stems and growth of leaves as well as coloring fruits.
6. Reduce the consumption of chemical agent, chemical fertilizer and insecticide.
7. Adjust the pH value of soil, chemical property and physical property.
8. Improve crop quality and the safety, increase production and store life.
9. Accelerate the decomposition and deterioration of organics.
10.Decomposed settled chemical fertilizer and chemical substance.
11.Able to free form the difficulty in consecutive planting.
12.Activate soil for long lasting cultivation.
13.Boost immunity and reduce disease infection rate.
1. Pot plant: Depends on the pot size, add 1-5 g per time, every 10-15 days.
2. Floral plants: 2-3 kgs for each 0.1 hectare, when used together with organic fertilizer as base fertilizer. Add 1kg 30-35days later as tracer.
3. Vegetable: 2-3 kgs for each 0.1 hectare, when used together with organic fertilizer as base fertilizer. Add 1kg 30-35days later as tracer. ( mix 3 kgs with 1 ton of compost well )
4. Fruit tree: According to the age and size of the tree, 3-5kgs / 0.1 hectare for basic fertilizer and tracer. ( mix 4 kgs with 1 ton of compost well )
5. Rootstalk: According to the age and size of the tree, 5kgs / 0.1 hectare for basic fertilizer and tracer. ( mix 5 kgs with 1 ton of compost well )
1. Pot plant, Floral plants, Vegetable :
(1) Spary 300-500 times dilution of Full Probio® on the leaves, every 7-10 days.
(2) Pour 300 times diluted Full Probio® to the soil in the pot / month.
2. Fruit tree, Rootstalk:
(1) Spary 500-1000 times dilution of Full Probio® on the leaves, every 10-15 days.
(2)Spary to the ground 300 times diluted Full Probio® solution, 3 liter for 0.1 hectare, on monthly basis.
1. Cabbage
Good performance on the cabbage, because the application of the solid microbial basal fertilizer and liquid Full Probio® during growth.
2. Bok-choy
(1) The barren field soil unused the Full Probio®microbial-fertilizer, led Bok-choy poor growth and vary in size.
(2) Harvesting of the relatively heavy weight in the Bok-choy, because the application of the solid Full Probio® and liquid Full Probio® during growth. (Right - to use / Left - unused)
(3) Plants size are more consistent on Bok-choy, because the application of the solid microbial basal fertilizer and liquid Full Probio® during growth. (Right - to use / Left - unused)
Full Probio®
4. Sweet potato vine
Application of the solid Full Probio®, make sweet potato leaf growth stable.
5. Broccoli
(1) The field soil unused the Full Probio®, resulting in a broccoli leaf chewing insects are serious.
(2) Foliage huge and intact in the broccoli, because the application of the solid Full Probio® and liquid Full Probio® during growth.
5. Mater convolvulus
(1) The field soil unused fertilizer, resulting in sparse plant.
(2) Mater convolvulus grow to more dense and higher, after use of liquid Full Probio® in growth phase.
(3) Harvesting of the relatively heavy weight in the Bok-choy, because the application of the liquid Full Probio® during growth. (Left – to use / Right - unused)
(4) Mater convolvulus grow to more dense, after use of liquid Full Probio® in growth phase. (Left – to use / Right - unused)
(5) Growth potential of roots is good, after use of liquid Full Probio® in growth phase. (Left – to use / Right - unused)
6. Pak-choi
(1) Pak-choi have lush green leaves, after use of liquid Full Probio® in growth phase.
(2) Harvesting of the relatively heavy weight in the pak-choy, after use of liquid Full Probio® in growth phase. (Right - to use / Left - un- used)
(3) Plants size are more consistent on Pak-choi, after use of liquid Full Probio® in growth phase. (Right - to use / Left - unused)
7. PWax apple
1. Influence of fruit color and palatability, after use liquid Full Probio® in the wax apple - Farmers diluted 500-fold liquid Full Probio® subjected to foliage spray in medium and small fruit period, the total administered twice within 20 days.
2. Liquid Full Probio® B.application and non-application of wax apple comparison. After applying the color more vivid, and the sweet-sour taste and ratio are better than not administered. Recommendation: often use perfusion liquid microbial fertilizer in the soil and foliar spray. (Left – to use / Right - unused)
3. Samples collected in southern Taiwan,Test time: non-production period in August, Significant differences can still be seen to improve the color, fruit status. 《top》
In Taiwan, the total of the agricultural waste is over 20 million tons per year, but treated less than 10%. It is important to treat them with advanced agricultural technology to convert them to be highly valued agricultural resources. When treating the organic waste with Full Probio®, it can be treat in aerboic and anerboic environment, it will absorb, decompose and eliminate the odorous content generated through the decomposition of ammonia or carbohydrate and make the organic waste without odor and finally completes decomposition of organic material. The organic fertilizer produced from this process contains high percentage organic material, nitrogen, phosphor, potassium and trace element requited by plants, and there are still lot of favorable microbes and growth hormone. It is able to improve the physical, chemical and biological properties of soil and help the healthy growth of crops, improve the quality and increase quantity.
Adding Full Probio® in the process will accelerate the decomposing of large molecular into small molecular and release energy to promote the generation from small molecular to the cells. Under aerobic condition, 50% of organic material will converted into carbon dioxide and water, and the other 50% will be generating into cells of probiotic.
The addition of probiotic during the composting process will cause the generation of nitrogen, phosphor and potassium.
Adding Full Probio® will reduce the ration between carbon and nitrogen and reduce the generation of ammonia so that reduce the lost of nitrogen.
Full Probio® can reduce the unpleasure odor. Adding Full Probio® in ordinary compost can reduce the fermentation duration to 45 days, which is about 50% of 90 days required in traditional composting. It has positive effects on the cost reduction. Promoting utilization of ware-house and quality of compost.
Lift bottle was the west water from original pool, without using Full Probio®, intermediate bottle was the west water using Full Probio® 1 week, and right one was the west water with using Full Probio® 2 weeks, and this bottle has no any odor.
